Unparalleled support and strengthening power for the liver*


Supports healthy liver function and the natural detoxification process.*

Helps increase L-Glutathione levels - an important antioxidant essential for the immune system's proper functioning.*

With more silybin (a nutrient that has been shown to protect liver cells) than 1200 mg of typical milk thistle.*


Take 2 capsules daily with water.


All of our products are backed by a 100% 90-day, money-back guarantee. Click here to view our full return policy.


Due to our commitment to innovation, sourcing the best available ingredients, and changes in how regulatory agencies require labels to be laid out, labels from different lots may vary slightly. Please note that while multiple formula versions of the same product may exist in the marketplace, this label represents the version currently being shipped. For the most accurate information regarding the product you receive, please refer to the label on the product packaging.


Western vs. Holistic Approach to Liver Health

We all know that the liver is the largest organ in the body. It is involved in over 500 functions. Among the most important of these is removing toxins from the body. If this is not done effectively, these toxins accumulate and ultimately lead to serious disease.

In holistic medicine, the liver is thought to control the flow of energy in the body and store blood. Poor energy flow leads to muscular tension, poor circulation, headaches, cold hands and feet, menstrual issues, and so on. The Liver System nourishes the tendons and ligaments, so stiffness, pain, and reduced mobility may accompany poor liver function. It is common for such stiffness and pain to be confused with joint problems. A weakened Liver System can also cause blurred vision, dry eyes, and glaucoma. Other issues include reduced sexual interest, soft, thin, brittle, pale, dull, and/or ridged nails, and a heightened risk for fungal infections.

Liver Supporting Nutrients

Every health enthusiast knows that milk thistle is extremely liver-supportive. But, there are vast differences between milk thistle supplements.

Milk thistle supports the liver via flavones that are collectively called “silymarin.” The most effective of these flavones is silybin. The problem with these flavones is that they are very poorly absorbed. However, absorption and delivery to liver cells increase by 800% when silybin is actively bound to phospholipids.

Like milk thistle, artichoke and bupleurum increase L-Glutathione levels in the liver. N-Acetyl Cysteine is the most effective L-Glutathione building block, and Alpha Lipoic Acid regenerates L-Glutathione so that each L-Glutathione molecule can do the work of many.

By helping relieve liver blockages, and through its cooling nature, the Bupleurum and Dong quai combination addresses the issues that holistic health systems identify as liver blockage and congestion.*

Complete Liver Support

LiverEssence™ provides 150 mg of Siliphos® in each day’s use. This provides 50 mg of pure silybin bound to 100 mg of phospholipids. Getting as much silybin to your liver cells would require more than 1200 mg of typical milk thistle preparations and cost three times more. It also includes every nutrient mentioned above to promote healthy liver function.*

LiverEssence™ is the only liver support system we know of that addresses liver health from both modern and holistic health perspectives. While either view is helpful in its own right, both together are far beyond either by itself.*

Featured Herbs & Ingredients


Research has shown that artichoke hinders the reproduction of liver cancer cells, protects against general liver toxins, decreases levels of bad fats and cholesterol in the liver, and promotes the free flow of bile.*


The most effective L-Glutathione building block. L-Glutathione is perhaps the most important weapon in the liver’s detoxification arsenal.*

Milk Thistle

One of the most profound herbal substances on earth. It helps cleanse the liver without the potential side effects of harsh, medicinal herbs.*


Ayurveda’s most profound brain tonic. Supports neurogenesis, problem-solving, learning, memory, and healthy stress response.*

Alpha Lipoic Acid

Extremely important in energy production. Without it, your cells cannot make ATP. It also regenerates L-Glutathione.*

Commitment to Purity

For more than 20 years, Pure Essence has led the natural supplement industry with innovation, creativity, and an unmatched commitment to purity.

Every raw material we use is hand selected and must be shown by sound science to serve a valid purpose in the overall action of the product it is added to. It must also be acceptable from the perspective of holistic health disciplines like Ayurveda and Traditional Chinese Medicine.

Not only is careful ingredient sourcing a priority to us, but also using the right tests to ensure safety and quality. Each batch is triple tested for identity, heavy metals, and toxins. Every product is 100% compliant with even the strictest of regulations.

Customer Reviews

Based on 11 reviews
betty hass-jones
Love this product!

It offer a real detoxing without the side effects that other items I have tried.

Great liver support!

You can’t beat the targeted liver support!! I love taking this blend. Makes a big difference.

Susan L.
Liver Essence is Great!

Excellent for my pet's liver health!

Five Stars

Great product

Sonia Dekker
Five Stars

This is definitely one of my favorite milk thistle products

Questions & Answers

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.